2. Neuronal Signaling Immunology/Inflammation
  3. Cholinesterase (ChE) NOD-like Receptor (NLR)
  4. SBN-284

SBN-284 (compound 3x) 是一种具有血脑透过性的胆碱酯酶 (Cholinesterases) 和 NLRP3 炎性体的双重抑制剂，对 EeAChE、hAChE、eqBChE 的 IC50 值分别为 0.37、0.31、0.29 μM，对 NLRP3 inflamm EC50 为 1 μM。SBN-284 可用于阿尔茨海默病的研究。

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SBN-284 Chemical Structure

SBN-284 Chemical Structure

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SBN-284 相关抗体

Top Publications Citing Use of Products

查看 Cholinesterase (ChE) 亚型特异性产品:

查看所有亚型
AChE BChE

查看 NOD-like Receptor (NLR) 亚型特异性产品:

查看所有亚型
NLRP3 NLRP1 NOD1 NOD2

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

SBN-284 (compound 3x) is a dual inhibitor of blood-brain permeable Cholinesterases and the NLRP3 inflammasome and is effective against EeAChE, hAChE and eqBChE, the IC50 values of are 0.37, 0.31, 0.29 μM respectively, and the EC50 of NLRP3 inflamm is 1 μM. SBN-284 can be used in Alzheimer's disease research[1].

IC50 & Target

EeAChE

0.37 μM (IC50)

hAChE

0.31 μM (IC50)

eqBCHE

0.29 μM (IC50)

NLRP3 inflammasome

1 μM (EC50)

分子量

585.73

Formula

C35H43N3O5
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

SBN-284 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SBN-284SBN284SBN 284Cholinesterase (ChE)NOD-like Receptor (NLR)ChENLRP3InhibitorAlzheimer's diseaseinhibitorinhibit

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产品名称：
SBN-284
目录号：
HY-159482
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