2. Immunology/Inflammation
  3. NOD-like Receptor (NLR)
  4. NOD1 antagonist-1

NOD1 antagonist-1 (compound 37) 对 NOD1 表现出拮抗性，对 NOD1/NOD2 具有微弱的选择性，IC50 分别是 9.18 μM 和 20.8 μM 。

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NOD1 antagonist-1 Chemical Structure

NOD1 antagonist-1 Chemical Structure

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NOD1 antagonist-1 相关抗体

Top Publications Citing Use of Products

查看 NOD-like Receptor (NLR) 亚型特异性产品:

查看所有亚型
NLRP3 NLRP1 NOD1 NOD2

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

NOD1 antagonist-1 (compound 37) exhibits an antagonistic activity towards NOD1 and a weak NOD1/NOD2 selectivity, with IC50s of 9.18 μM and 20.8 μM, respectively[1].

IC50 & Target

NOD1

9.18 μM (IC50)

NOD2

20.8 μM (IC50)

体外研究
(In Vitro)

NOD1 antagonist-1 (25 μM，1 h) 抑制 HEK-Blue 细胞中 NF-kB 被转录激活，具有低毒性(25 μM，18 h)[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

NOD1 antagonist-1 相关抗体:

Cell Cytotoxicity Assay[1]

Cell Line: HEK-Blue
Concentration: 25 μM
Incubation Time: 18 h
Result: Maintained a residual metabolic activity of over 80%.
分子量

440.60

Formula

C24H32N4O2S
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

NOD1 antagonist-1 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

NOD1 antagonist-1NOD-like Receptor (NLR)Noditinib-1NF-kBHEK BlueInhibitorinhibitorinhibit

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产品名称：
NOD1 antagonist-1
目录号：
HY-163274
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