2. Immunology/Inflammation
  3. NOD-like Receptor (NLR)
  4. NLRP3-IN-58

NLRP3-IN-58 (Compound DS15) 是 NLRP3 炎症小体 (NLRP3 inflammasome) 激活的抑制剂，IC50 为 3.85 μM，在 10 μM 浓度下可抑制 33% 的 IL-1β 释放。

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NLRP3-IN-58 Chemical Structure

NLRP3-IN-58 Chemical Structure

CAS No. : 2956014-05-2

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NLRP3-IN-58 相关抗体

Top Publications Citing Use of Products

查看 NOD-like Receptor (NLR) 亚型特异性产品:

查看所有亚型
NLRP3 NLRP1 NOD1 NOD2

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

NLRP3-IN-58 (Compound DS15) is an inhibitor for the activation of NLRP3 inflammasome with an IC50 of 3.85 μM, and inhibits 33% IL-1β release at a concentration of 10 μM[1].

分子量

439.91

Formula

C22H18ClN3O3S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

NLRP3-IN-58 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

NLRP3-IN-582956014-05-2NOD-like Receptor (NLR)Inhibitorinhibitorinhibit

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产品名称：
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目录号：
HY-168561
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