1. Neuronal Signaling
  2. Serotonin Transporter
  3. Norfenfluramine

Norfenfluramine  (Synonyms: 去甲氟苯丙胺; (±)-Norfenfluramine)

目录号: HY-118010
产品使用指南

Norfenfluramine ((±)-Norfenfluramine) 是 Fenfluramine 的主要的代谢物,可透过血脑屏障。 Norfenfluramine 可以与 5-HT 转运蛋白相互作用,从神经元中释放 5-HT。Norfenfluramine 在体内表现出抗癫痫作用。

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Norfenfluramine Chemical Structure

Norfenfluramine Chemical Structure

CAS No. : 1886-26-6

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Other Forms of Norfenfluramine:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Norfenfluramine ((±)-Norfenfluramine) is a major and brain-penetrant metabolite of Fenfluramine. Norfenfluramine can interact with 5-HT transporters to release 5-HT from neurons. Norfenfluramine displays antiepileptic effects in vivo[1][2].

体外研究
(In Vitro)

(±)-Norfenfluramine interacts with 5-hydroxytryptamine (5-HT) transporters to release 5-HT from neurons[1].
(±)-Norfenfluramine increases [3H]dopamine and [3H] norepinephrine release in vitro[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

203.20

Formula

C10H12F3N

CAS 号
中文名称

去甲氟苯丙胺

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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目录号:
HY-118010
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