1. Metabolic Enzyme/Protease
  2. NADPH Oxidase
  3. NOX2-IN-2

NOX2-IN-2 (compound 33) 是一种有效的 NOX2 抑制剂,靶向 p47phox-p22phox 蛋白质-蛋白质相互作用,Ki 为 0.24 μM。NOX2-IN-2 抑制细胞中 NOX2 产生的 ROS。

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NOX2-IN-2 Chemical Structure

NOX2-IN-2 Chemical Structure

CAS No. : 2648709-79-7

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生物活性

NOX2-IN-2 (compound 33) is a potent NOX2 inhibitor targeting the p47phox-p22phox protein-protein interaction with a Ki of 0.24 μM. NOX2-IN-2 inhibits ROS production derived from NOX2 in cells[1].

分子量

471.51

Formula

C25H25N7O3

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
NOX2-IN-2
目录号:
HY-156425
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