1. Membrane Transporter/Ion Channel
  2. Chloride Channel
  3. NS5818

NS5818 是一种有效的氯离子通道 (chloride channel) 抑制剂。NS5818 可抑制酸化和骨吸收。NS5818 具有研究骨质疏松症的潜力。

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NS5818 Chemical Structure

NS5818 Chemical Structure

CAS No. : 674299-39-9

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规格 是否有货
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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

NS5818 is a potent chloride channel inhibitor. NS5818 inhibits acidification and bone resorption. NS5818 has the potential for the research of osteoporosis[1].

体外研究
(In Vitro)

NS5818 (50 µM; 6 days) 可抑制破骨细胞吸收区室的酸化和骨吸收,对人类破骨细胞骨吸收的 IC50 值为 5µM[1]
NS5818 (10 µM; 20 days) 可抑制在牛骨切片上培养的成熟破骨细胞的骨吸收[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

496.35

Formula

C23H19Cl2N7O2

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
NS5818
目录号:
HY-122077
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