1. Metabolic Enzyme/Protease
  2. Acyltransferase
  3. NTE-122 dihydrochloride

NTE-122 (diHClide) 是一种酰基辅酶A:胆固醇酰基转移酶 (acyltransferase) (ACAT) 抑制剂,在高胆固醇饲养兔子肝脏和主动脉中的 IC50 分别为 7.6nM、4.4nM 和 9.6nM,在动脉粥样硬化中发挥着重要作用。

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NTE-122 dihydrochloride Chemical Structure

NTE-122 dihydrochloride Chemical Structure

CAS No. : 166967-84-6

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生物活性

NTE-122 (dihydrochloride) is an inhibitor of acyl-CoA:cholesterol acyltransferase (ACAT), with the IC50 in liver and aorta of cholesterol-fed rabbits of 7.6nM, 4.4nM and 9.6 nM, respectively, that plays an important role in atherosclerosis[1].

分子量

703.83

Formula

C38H60Cl2N6O2

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
NTE-122 dihydrochloride
目录号:
HY-121762
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