1. Membrane Transporter/Ion Channel
  2. EAAT
  3. Nε-(Carboxyethyl)lysine

Nε-(Carboxyethyl)lysine 是一种晚期糖基化终产物 (AGE)。Nε-(Carboxyethyl)lysine 导致蛋白质之间的交联,进而影响蛋白质的结构和功能,导致蛋白质变性。Nε-(Carboxyethyl)lysine 与 RAGE 受体结合,影响细胞信号传导,调节炎症反应、细胞增殖和凋亡等过程。Nε-(Carboxyethyl)lysine 影响谷氨酸转运蛋白,减少谷氨酸摄取和S100B蛋白分泌,影响神经系统中的神经传递,并表现出糖尿病相关的神经毒性。

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Nε-(Carboxyethyl)lysine Chemical Structure

Nε-(Carboxyethyl)lysine Chemical Structure

CAS No. : 5746-03-2

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Other Forms of Nε-(Carboxyethyl)lysine:

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生物活性

Nε-(Carboxyethyl)lysine is an advanced glycation end product (AGE). Nε-(Carboxyethyl)lysine causes cross-linking between proteins, affects the structure and function of proteins, and leads to protein denaturation. Nε-(Carboxyethyl)lysine binds to RAGE receptors, affects cell signaling, regulates processes such as inflammatory response, cell proliferation and apoptosis. Nε-(Carboxyethyl)lysine affects glutamate transporter, reduces glutamate uptake and S100B protein secretion, affects neurotransmission in the nervous system, and exhibits diabetic-related neurotoxicity[1][2].

分子量

218.25

Formula

C9H18N2O4

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

Nε-(Carboxyethyl)lysine 相关分类

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