2. Metabolic Enzyme/Protease Cell Cycle/DNA Damage
  3. HIF/HIF Prolyl-Hydroxylase HSP
  4. O-Carboranylphenoxyacetanilide

O-Carboranylphenoxyacetanilide 

目录号: HY-D2360
产品使用指南

摩尔计算器

O-Carboranylphenoxyacetanilide 是一种 HIF-1α 抑制剂，可抑制 HIF-1α 活化。O-Carboranylphenoxyacetanilide 可抑制 HeLa 细胞中 HIF 的转录活性 (IC50: 0.74 μM)。O-Carboranylphenoxyacetanilide 可抑制 HSP60 分子伴侣活性和 HSP60 ATPase 活性。

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O-Carboranylphenoxyacetanilide Chemical Structure

O-Carboranylphenoxyacetanilide Chemical Structure

CAS No. : 1220716-15-3

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O-Carboranylphenoxyacetanilide 相关抗体

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查看 HIF/HIF Prolyl-Hydroxylase 亚型特异性产品:

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HIF-1α HIF

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HSP40 HSP70 HSP90 HSP105 HSF1 HSP HSPA5

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

O-Carboranylphenoxyacetanilide is a HIF-1α inhibitor and inhibits HIF-1α activation. O-Carboranylphenoxyacetanilide inhibits transcriptional activity of HIF in HeLa cells (IC50: 0.74 μM). O-Carboranylphenoxyacetanilide inhibits HSP60 chaperone activity and HSP60 ATPase activity[1].

IC50 & Target[1]

HIF-1α

 

分子量

429.29

Formula

C16H24B11NO5
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

O-Carboranylphenoxyacetanilide 相关分类

  • 摩尔计算器

  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

O-Carboranylphenoxyacetanilide1220716-15-3HIF/HIF Prolyl-HydroxylaseHSPHypoxia-inducible factorsHIFsHIF-PHHeat shock proteinsHSP60HIF-1αInhibitorinhibitorinhibit

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