1. 天然产物
  2. 植物 酚类
  3. 藤黄科 氧杂蒽酮
  4. 云树
  5. O-Demethylforbexanthone

O-Demethylforbexanthone (7,9,12-Trihydroxy-2,2-dimethyl-2H,6H-pyrano[3,2-b]xanthen-6-one) 是一种黄酮,可以从藤黄属植物中分离得到。

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O-Demethylforbexanthone Chemical Structure

O-Demethylforbexanthone Chemical Structure

CAS No. : 92609-77-3

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  • 生物活性

  • 纯度 & 产品资料

生物活性

O-Demethylforbexanthone (7,9,12-Trihydroxy-2,2-dimethyl-2H,6H-pyrano[3,2-b]xanthen-6-one) is a Triterpenoids product that can be isolated from the herbs of Jatropha curcas.[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
HCT-116 IC50
4.7 μM
Compound: 3
Cytotoxicity against human HCT116 cells assessed as decrease in cell viability after 72 hrs by MTT assay
Cytotoxicity against human HCT116 cells assessed as decrease in cell viability after 72 hrs by MTT assay
[PMID: 24754786]
HCT-15 IC50
5.1 μM
Compound: 3
Cytotoxicity against human HCT15 cells assessed as decrease in cell viability after 72 hrs by MTT assay
Cytotoxicity against human HCT15 cells assessed as decrease in cell viability after 72 hrs by MTT assay
[PMID: 24754786]
HeLa IC50
4.9 μM
Compound: 3
Cytotoxicity against human HeLa cells assessed as decrease in cell viability after 72 hrs by MTT assay
Cytotoxicity against human HeLa cells assessed as decrease in cell viability after 72 hrs by MTT assay
[PMID: 24754786]
HepG2 IC50
10.1 μM
Compound: 3
Cytotoxicity against human HepG2 cells assessed as decrease in cell viability after 72 hrs by MTT assay
Cytotoxicity against human HepG2 cells assessed as decrease in cell viability after 72 hrs by MTT assay
[PMID: 24754786]
MCF7 IC50
11.7 μM
Compound: 3
Cytotoxicity against human MCF7 cells assessed as decrease in cell viability after 72 hrs by MTT assay
Cytotoxicity against human MCF7 cells assessed as decrease in cell viability after 72 hrs by MTT assay
[PMID: 24754786]
MCF7 IC50
34.4 μM
Compound: 3
Cytotoxicity against human MCF7 cells overexpressing HER2 assessed as decrease in cell viability after 72 hrs by MTT assay
Cytotoxicity against human MCF7 cells overexpressing HER2 assessed as decrease in cell viability after 72 hrs by MTT assay
[PMID: 24754786]
MDA-MB-435 IC50
3.9 μM
Compound: 3
Cytotoxicity against human MDA-MB-435 cells assessed as decrease in cell viability after 72 hrs by MTT assay
Cytotoxicity against human MDA-MB-435 cells assessed as decrease in cell viability after 72 hrs by MTT assay
[PMID: 24754786]
分子量

326.30

Formula

C18H14O6

CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
O-Demethylforbexanthone
目录号:
HY-N3158
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