2. Anti-infection
  3. Bacterial
  4. Octenidine

Octenidine  (Synonyms: 奥替尼啶)

目录号: HY-B2170
产品使用指南

摩尔计算器

Octenidine 是一种有效的抗菌剂，对多耐药性格兰仕阴性病原菌有抑制活性。Octenidine 能抑制生物膜基因表达并破坏生物膜的形成。

在相同的摩尔浓度下，化合物盐形式与游离形式有相同的生物活性，但盐形式 Octenidine dihydrochloride 通常具有更好的水溶性和稳定性。

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Octenidine Chemical Structure

Octenidine Chemical Structure

CAS No. : 71251-02-0

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规格 是否有货
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Octenidine 的其他形式现货产品:

Customer Review

Other Forms of Octenidine:

Octenidine 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Octenidine is a potent antibacterial agent, possessing activity against multidrug-resistant Gram-negative pathogens. Octenidine can inhibit the expression of biofilm genes and destroy the formation of biofilms[1][3].

体外研究
(In Vitro)

Octenidine has antimicrobial activity against multidrug-resistant Gram-negative pathogens[1].

Escherichia coli Pseudomonas aeruginosa
WT CTX-M-1 CTX-M-15 NDM-1 VIM-15 WT PER-1 VEB-1 OprD VIM-2
MIC (mg/L) 0.5 2.5 1.2 5 2.5 10 40 40 40 40

Octenidine (0-20 h) retardants P. aeruginosa growth in prolonged exposure condition[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Octenidine 相关抗体:
体内研究
(In Vivo)

Octenidine reduces bacterial counts on mice wounds and inhibit meticillin-resistant Staphylococcus aureus (MRSA)[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Mice (a six-millimetre punch full-thickness wound was inoculated with MRSA suspension)[3]
Dosage:
Administration: Administrated once 24 hours post-wounding
Result: Accelerated healing and reduced by >3.6 log cfu/g bacterial counts on the wounds relative to the PBS-treated control.
Exhibited lower burden of the inflammatory cells, more mature collagen fibres and well-defined epithelialisation.
Inhibited the expression of MRSA and its biofilm genes by nearly 100%.
Clinical Trial
分子量

550.90

Formula

C36H62N4
CAS 号
中文名称

奥替尼啶
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Octenidine 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Octenidine71251-02-0奥替尼啶Bacterialantibacterialmultidrug-resistantGram-negativeMRSAbiofilmInhibitorinhibitorinhibit

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