2. Membrane Transporter/Ion Channel
  3. Na+/K+ ATPase
  4. Oleandrigenin

Oleandrigenin  (Synonyms: 夹竹桃苷元)

目录号: HY-N11690
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Oleandrigenin 是一种有效的强心类固醇。Oleandrigenin 显示 Na+/K+-ATP 酶抑制和细胞毒性活性。

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Oleandrigenin Chemical Structure

Oleandrigenin Chemical Structure

CAS No. : 465-15-6

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Oleandrigenin 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Oleandrigenin is a potent cardiotonic steroid. Oleandrigenin shows Na+/K+-ATP-ase inhibiting and cytotoxic activities[1][2].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
A549 IC50
> 100 μM
Compound: 12
Viability of human A549 cells by MTT assay after 24 hrs
Viability of human A549 cells by MTT assay after 24 hrs
[PMID: 17595134]
A549 IC50
0.36 μM
Compound: 12
Inhibition of induction of ICAM1 expression in human A549 cells in presence of TNFalpha after 1 hr
Inhibition of induction of ICAM1 expression in human A549 cells in presence of TNFalpha after 1 hr
[PMID: 17595134]
A549 IC50
0.52 μM
Compound: 12
Inhibition of induction of ICAM1 expression in human A549 cells in presence of IL1-alpha after 1 hr
Inhibition of induction of ICAM1 expression in human A549 cells in presence of IL1-alpha after 1 hr
[PMID: 17595134]
BJ IC50
0.1 μM
Compound: 2
Cytotoxicity against human BJ cells assessed as reduction in cell viability incubated for 72 hrs by resazurin assay
Cytotoxicity against human BJ cells assessed as reduction in cell viability incubated for 72 hrs by resazurin assay
[PMID: 32645647]
BJ IC50
0.1 μM
Compound: 2
Cytotoxicity against human BJ cells assessed as reduction in cell viability after 72 hrs by resazurin dye based assay
Cytotoxicity against human BJ cells assessed as reduction in cell viability after 72 hrs by resazurin dye based assay
[PMID: 31325787]
CCRF-CEM IC50
0.2 μM
Compound: 2
Cytotoxicity against human CEM cells assessed as reduction in cell viability incubated for 72 hrs by resazurin assay
Cytotoxicity against human CEM cells assessed as reduction in cell viability incubated for 72 hrs by resazurin assay
[PMID: 32645647]
CCRF-CEM IC50
0.2 μM
Compound: 2
Antiproliferative activity against human CEM cells assessed as reduction in cell viability after 72 hrs by resazurin dye based assay
Antiproliferative activity against human CEM cells assessed as reduction in cell viability after 72 hrs by resazurin dye based assay
[PMID: 31325787]
HeLa IC50
0.2 μM
Compound: 2
Cytotoxicity against human HeLa cells assessed as reduction in cell viability incubated for 72 hrs by resazurin assay
Cytotoxicity against human HeLa cells assessed as reduction in cell viability incubated for 72 hrs by resazurin assay
[PMID: 32645647]
HeLa IC50
0.2 μM
Compound: 2
Antiproliferative activity against human HeLa cells assessed as reduction in cell viability after 72 hrs by resazurin dye based assay
Antiproliferative activity against human HeLa cells assessed as reduction in cell viability after 72 hrs by resazurin dye based assay
[PMID: 31325787]
MCF7 IC50
0.8 μM
Compound: 2
Cytotoxicity against human MCF7 cells assessed as reduction in cell viability incubated for 72 hrs by resazurin assay
Cytotoxicity against human MCF7 cells assessed as reduction in cell viability incubated for 72 hrs by resazurin assay
[PMID: 32645647]
MCF7 IC50
0.8 μM
Compound: 2
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by resazurin dye based assay
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by resazurin dye based assay
[PMID: 31325787]
分子量

432.55

Formula

C25H36O6
CAS 号
中文名称

夹竹桃苷元
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Oleandrigenin 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Oleandrigenin465-15-6夹竹桃苷元Na+/K+ ATPaseSodium potassium pumpCEMMCF7HeLaBJ cellsInhibitorinhibitorinhibit

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