2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. iGluR
  4. Oleoyl-D-lysine

Oleoyl-D-lysine 是一种基于脂质的、选择性的甘氨酸转运体-2 (GlyT2) 抑制剂。Oleoyl-D-lysine 可逆转小鼠神经性疼痛，对慢性神经性疼痛有抗嗜睡的作用。Oleoyl-D-lysine 安全有效，不会引起呼吸抑制。

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Oleoyl-D-lysine Chemical Structure

Oleoyl-D-lysine Chemical Structure

CAS No. : 2240164-55-8

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Oleoyl-D-lysine 相关抗体

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AMPA Receptor NMDA Receptor Kainate Receptor

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Oleoyl-D-lysine is a selective Glycine Transporter-2 (GlyT2) inhibitor based on lipid. Oleoyl-D-lysine reverses neuropathic pain in mice, shows antidrowsiness effect on chronic neuropathic pain. Oleoyl-D-lysine is safe and effective without respiratory depression[1].

IC50 & Target

Glycine Transporter-2 (GlyT2)[1]
体内研究
(In Vivo)

Oleoyl-D-lysine effectively reverses neuropathic pain in a mouse model of chronic neuropathic (chronic constriction injury) pain, reaching a peak analgesic dose of 30 mg/kg without causing respiratory depression; resultig mild side effects at 100 mg/kg without causing convulsions[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

410.63

Formula

C24H46N2O3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Oleoyl-D-lysine 相关分类

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Keywords:

Oleoyl-D-lysine2240164-55-8iGluRIonotropic glutamate receptorsInhibitorinhibitorinhibit

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