2. GPCR/G Protein
  3. Prostaglandin Receptor
  4. ONO-AE3-208 sodium salt

ONO-AE3-208 sodium salt  (Synonyms: AE 3-208 sodium salt)

目录号: HY-50901A
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摩尔计算器

ONO-AE3-208 (sodium salt) 是一种选择性和口服活性的 EP4 受体拮抗剂，Ki 为 1.3 nM。ONO-AE3-208 (sodium salt) 对 EP3、FP 和 TP 受体的影响较小 (Ki 分别为 30 nM、790 nM 和 2400 nM)。ONO-AE3-208 (sodium salt) 抑制前列腺癌的细胞侵袭、迁移和转移。

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ONO-AE3-208 sodium salt Chemical Structure

ONO-AE3-208 sodium salt Chemical Structure

CAS No. : 2309931-05-1

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ONO-AE3-208 sodium salt 的其他形式现货产品:

Other Forms of ONO-AE3-208 sodium salt:

ONO-AE3-208 sodium salt 相关抗体

Top Publications Citing Use of Products

    ONO-AE3-208 sodium salt purchased from MCE. Usage Cited in: Hypertension. 2014 Aug;64(2):369-77.  [Abstract]

    Effect of EP4 antagonists on AngII-induced PRR protein expression in primary IMCD cells. PRR protein expression is analyzed by immunoblotting. (A and B) Representative PRR immunoblot from 2-3 independent experiments.

    查看 Prostaglandin Receptor 亚型特异性产品:

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    DP EP FP IP TXA2/TP TXB2

    • 生物活性

    • 纯度 & 产品资料

    • 参考文献

    生物活性

    ONO-AE3-208 (sodium salt) is a selective and orally active EP4 receptor antagonist with a Ki of 1.3 nM. ONO-AE3-208 (sodium salt) shows less potently affects EP3, FP, and TP receptors (Ki of 30 nM, 790 nM, and 2400 nM, respectively). ONO-AE3-208 (sodium salt) suppresses cell invasion, migration, and metastasis of prostate cancer[1][2].

    分子量

    426.42

    Formula

    C24H20FN2NaO3
    CAS 号
    运输条件

    Room temperature in continental US; may vary elsewhere.
    储存方式

    Please store the product under the recommended conditions in the Certificate of Analysis.
    纯度 & 产品资料
    参考文献

    ONO-AE3-208 sodium salt 相关分类

    • 摩尔计算器

    • 稀释计算器

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    Help & FAQs
    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    ONO-AE3-2082309931-05-1AE 3-208Prostaglandin ReceptorInhibitorinhibitorinhibit

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