2. Anti-infection
  3. RABV
  4. Ormutivimab

Ormutivimab  (Synonyms: 奥木替韦单抗; NM57; rhRIG)

目录号: HY-P99792
技术支持

Ormutivimab (rhRIG) 是一种重组人单克隆抗体，靶向狂犬病病毒。Ormutivimab 可中和多种狂犬病病毒株。Ormutivimab 对狂犬病暴露后预防 (PEP) 模型具有强大的效力。

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CAS No. : 2449086-91-1

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Ormutivimab 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Ormutivimab (rhRIG) is a recombinant human monoclonal antibody, targeting rabies virus. Ormutivimab neutralizes a variety of rabies virus strains. Ormutivimab exhibits potent potency against rabies post-exposure prophylaxis (PEP) model[1][2].

同型

Human IgG1 lambda1
推荐同型对照抗体
种属

Human
体内研究
(In Vivo)

Ormutivimab (20 IU/kg；肌肉注射；单剂量) 保护比格犬免受 RABV BD06 的致命攻击[1]。
Ormutivimab (20 IU/kg、100 IU/kg；肌注；单剂量) 保护受攻击的 Kunming 小鼠免受各种狂犬病病毒的侵害[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Balb/c mice challenge model with rabies virus[1]
Dosage: 20 IU/kg, 100 IU/kg
Administration: Intramuscular injection; single dose after 4 hr after infection
Result: Protected mice from rabies CVS-24 and GZ-1 isolates at a comparable rate (90%) to that of HRIG, human antirabies immune globulin.
CAS 号
中文名称

奥木替韦单抗
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • Human IgG1 lambda2
纯度 & 产品资料
参考文献

Ormutivimab 相关分类

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ormutivimab2449086-91-1NM57 rhRIG奥木替韦单抗NM 57NM-57RABVRabies VirusInhibitorinhibitorinhibit

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