2. Membrane Transporter/Ion Channel
  3. P-glycoprotein
  4. P-gp inhibitor 13

P-gp inhibitor 13 是一种 P-gp 抑制剂。 P-gp inhibitor 13 可以逆转 A2780/T 细胞中 P-糖蛋白介导的紫杉醇耐药性。P-gp inhibitor 13 可用于晚期急性髓性白血病的研究。

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P-gp inhibitor 13 Chemical Structure

P-gp inhibitor 13 Chemical Structure

CAS No. : 3041121-57-4

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P-gp inhibitor 13 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

P-gp inhibitor 13 is a P-gp inhibitor. P-gp inhibitor 13 can reverse P-glycoprotein-mediated paclitaxel resistance in A2780/T cell. P-gp inhibitor 13 can be used for the research of advanced acute myeloid leukemia[1].
体外研究
(In Vitro)

P-gp inhibitor 13 (Compound 27f) 在 A2780/T 细胞中表现出显着的化学敏感性，IC50 值为 0.010 μM[1]。
P-gp inhibitor 13 通过抑制 P-gp 有效增加紫杉醇和罗丹明123的积累，逆转多药耐药[1]。
P-gp inhibitor 13 几乎没有相关的心脏毒性[1]。
P-gp inhibitor 13（2.5 μM、5 μM、10 μM、20 μM）在 A2780/T 细胞中表现出浓度依赖性 MDR 逆转活性[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

P-gp inhibitor 13 相关抗体:
分子量

546.61

Formula

C32H34O8
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

P-gp inhibitor 13 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

P-gp inhibitor 133041121-57-4P-glycoproteinP-gpPgpMultidrug resistance protein 1MDR1ATP-binding cassette sub-family B member 1ABCB1Cluster of differentiation 243CD243P-glycoprotein transporteradvanced acute myeloid leukemiaInhibitorinhibitorinhibit

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