2. NF-κB Metabolic Enzyme/Protease Immunology/Inflammation
  3. Keap1-Nrf2 Reactive Oxygen Species
  4. PACA

PACA 是神经生长因子诱导的神经突生长的增强剂，通过激活 Nrf2/HO-1 通路增强神经生长因子 (NGF) 诱导的神经突生长并减弱 6-羟多巴胺 (6-OHDA) 诱导的毒性。PACA 具有神经保护和神经生成活性。PACA 可用于改善 MPTP 小鼠帕金森病模型和 MPP+ 诱导神经元的多巴胺能神经元损失和运动功能障碍的研究。

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PACA Chemical Structure

PACA Chemical Structure

CAS No. : 1431724-30-9

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PACA 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

PACA is an enhancer of nerve growth factor-induced neurite outgrowth, enhancing nerve growth factor (NGF)-induced neurite outgrowth and attenuating 6-hydroxydopamine (6-OHDA)-induced toxicity by activating the Nrf2/HO-1 pathway. PACA has neuroprotective and neurogenic activities. PACA can be used to improve dopaminergic neuron loss and motor dysfunction in MPTP mouse models of Parkinson's disease and MPP+-induced neurons[1][2].

分子量

217.22

Formula

C12H11NO3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

PACA 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PACA1431724-30-9Keap1-Nrf2Reactive Oxygen SpeciesNGFNrf2/HO-1MPTP Mouse ModelNeuroprotectionInhibitorinhibitorinhibit

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