2. GPCR/G Protein
  3. Protease Activated Receptor (PAR)
  4. PAR3 (1-6) (human)

PAR3 (1-6) (human)  (Synonyms: TFRGAP)

目录号: HY-P2380
产品使用指南

摩尔计算器

PAR3 (1-6) 是蛋白酶激活受体 1 (PAR1) 的合成肽激动剂，对应于人类 PAR3 氨基末端束缚配体序列的残基 1-6 和全长人类序列的残基 39-44。PAR3 (1-6) 激活表达 PAR1 但不表达 PAR3 的成纤维细胞中的 p42/44 MAPK 信号传导，这种作用可被 PAR1 拮抗剂 RWJ 56110.1 阻断。

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Custom Peptide Synthesis

PAR3 (1-6) (human) Chemical Structure

PAR3 (1-6) (human) Chemical Structure

CAS No. : 320347-28-2

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PAR3 (1-6) (human) 相关抗体

Top Publications Citing Use of Products

查看 Protease Activated Receptor (PAR) 亚型特异性产品:

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PAR1 PAR2 PAR4

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

PAR3 (1-6) is a synthetic peptide agonist of proteinase-activated receptor 1 (PAR1) that corresponds to residues 1-6 of the amino terminal tethered ligand sequence of human PAR3 and residues 39-44 of the full-length human sequence. PAR3 (1-6) activates p42/44 MAPK signaling in fibroblasts expressing PAR1, but not PAR3, an effect that can be blocked by the PAR1 antagonist RWJ 56110.

分子量

647.72

Formula

C29H45N9O8
CAS 号
Sequence

Thr-Phe-Arg-Gly-Ala-Pro
Sequence Shortening

TFRGAP
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

PAR3 (1-6) (human) 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PAR3 (1-6) (human)320347-28-2TFRGAPProtease Activated Receptor (PAR)Thrombin receptorsInhibitorinhibitorinhibit

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