1. Immunology/Inflammation
  2. PD-1/PD-L1
  3. PD-1/PD-L1-IN 5 TFA

PD-1/PD-L1-IN 5 TFA 是一种有效的 PD-1/PD-L1 蛋白/蛋白相互作用抑制剂,IC50 ≤100 nM。详细信息请参考专利文献 WO2017222976A1 中的化合物 Example 1。

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PD-1/PD-L1-IN 5 TFA Chemical Structure

PD-1/PD-L1-IN 5 TFA Chemical Structure

CAS No. : 2170209-52-4

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Other Forms of PD-1/PD-L1-IN 5 TFA:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

PD-1/PD-L1-IN 5 TFA is a PD-1/PD-L1 protein/protein interaction inhibitor extracted from patent WO2017222976A1, compound Example 1, has an IC50 of ≤100 nM[1].

IC50 & Target

IC50: ≤100 nM (PD-1/PD-L1)[1]

体外研究
(In Vitro)

The compounds modulate PD-1/PD-L1 protein/protein interaction and are useful in the treatment of various diseases including infectious diseases and cancer. The compounds can be used as immunomodulators[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Formula

C22H18N4O3S.xC2HF3O2

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
PD-1/PD-L1-IN 5 TFA
目录号:
HY-129172
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