2. GPCR/G Protein Neuronal Signaling
  3. Cholecystokinin Receptor
  4. PD 136450

PD 136450  (Synonyms: CAM 1189)

目录号: HY-120381
产品使用指南

摩尔计算器

PD 136450 (CAM 1189) 是胆囊收缩素 2 (CCK2) 的拮抗剂。PD 136450 表现出抗分泌、抗焦虑和抗溃疡活性，抑制大鼠胃酸分泌 (IC50=1 mg/kg)，并改善出血性病变 (IC50=4.7 mg/kg)。

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PD 136450 Chemical Structure

PD 136450 Chemical Structure

CAS No. : 139067-52-0

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PD 136450 相关抗体

Top Publications Citing Use of Products

查看 Cholecystokinin Receptor 亚型特异性产品:

查看所有亚型
CCKAR CCKBR

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

PD 136450 (CAM 1189) is an antagonist for cholecystokinin 2 (CCK2). PD 136450 exhibits anti-secretory, anxiolytic and anti-ulcer activities, inhibits gastric acid secretion (IC50=1 mg/kg), and ameliorates the haemorrhagic lesions (IC50=4.7 mg/kg) in rats[1].

分子量

612.72

Formula

C35H40N4O6
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

PD 136450 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PD 136450139067-52-0CAM 1189PD136450PD-136450CAM1189CAM-1189Cholecystokinin ReceptorCCK Receptoranti-secretoryanxiolyticanti-ulcerhemorrhagic lesionWistar ratInhibitorinhibitorinhibit

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