2. 天然产物
  3. 萜类 微生物
  4. 二萜
  5. Peniditerpenoid A

Peniditerpenoid A 是一种二开环吲哚二萜。Peniditerpenoid A 可降低 RANKL 诱导的 p-IkBα 的表达。Peniditerpenoid A 可抑制 RANKL 诱导的破骨细胞分化。Peniditerpenoid A 具有研究骨质疏松症的潜力。

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Peniditerpenoid A Chemical Structure

Peniditerpenoid A Chemical Structure

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Peniditerpenoid A 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Peniditerpenoid A is a di-seco-indole diterpenoid. Peniditerpenoid A decreases the expression of p-IkBαby RANKL induced. Peniditerpenoid A inhibits RANKL induced osteoclast differentiation. Peniditerpenoid A has the potential for the research of osteoporosis[1].

体外研究
(In Vitro)

Peniditerpenoid A (compound 1) (5, 10, 20 µM) 以剂量依赖性方式抑制 RANKL 诱导的破骨细胞分化[1]。
Peniditerpenoid A (5, 10, 20 µM) 降低 RAW264.7 细胞中 p-IkBα 的表达[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Peniditerpenoid A 相关抗体:

Western Blot Analysis[1]

Cell Line: RAW264.7 cells
Concentration: 5, 10, 20 µM
Incubation Time: 4h+RANKL (100 ng/mL) for 30 min or 24 h
Result: Reduced IκBα phosphorylation, elevated cytoplasmic p65 and inhibited p65 nuclear translocation.
分子量

483.55

Formula

C27H33NO7
结构分类
初始来源

Mangrove Sediment-Derived Penicillium sp.
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Peniditerpenoid A 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Peniditerpenoid AOthersRAW264.7 cellsp-IkBαosteoclastp65osteoporosisInhibitorinhibitorinhibit

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