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  4. Perfluoroenanthic acid

Perfluoroenanthic acid  (Synonyms: 全氟庚酸; Perfluoroheptanoic acid; Tridecafluoroheptanoic acid; PFHpA)

目录号: HY-21197
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Perfluoroenanthic acid (Perfluoroheptanoic acid) 是一种全氟烷基物质 (PFAS)，妊娠期暴露会对子代小鼠精管发育和睾丸m6A RNA 甲基化产生不利影响，进而干扰精子发生，导致生殖毒性。Perfluoroenanthic acid 在初级皮层神经元培养中改变树突棘的形态发生和突触形成，增强神经活动和突触传递，升高兴奋性突触相关蛋白 Synaptophysin 和 PSD95 的表达。

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Perfluoroenanthic acid Chemical Structure

Perfluoroenanthic acid Chemical Structure

CAS No. : 375-85-9

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Perfluoroenanthic acid 相关抗体

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  • 生物活性

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生物活性

Perfluoroenanthic acid (Perfluoroheptanoic acid) is a type of perfluoroalkyl substance (PFAS) that can negatively impact the development of seminiferous tubules and m6A RNA methylation in the testes of offspring mice when exposed during pregnancy, consequently disrupting spermatogenesis and leading to reproductive toxicity. Perfluoroenanthic acid alters the morphology of dendritic spines and synaptic formation in primary cortical neuron cultures, enhancing neuronal activity and synaptic transmission, and increasing the expression of excitatory synapse-related proteins Synaptophysin and PSD95[1][2].

分子量

364.06

Formula

C7HF13O2
CAS 号
中文名称

全氟庚酸
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Perfluoroenanthic acid 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Perfluoroenanthic acid375-85-9Perfluoroheptanoic acid Tridecafluoroheptanoic acid PFHpA全氟庚酸OthersPerfluoroalkyl substancespregnancymouse seminiferous tubules and testesspermatogenesisdendritic spinessynapsesneural activityInhibitorinhibitorinhibit

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