2. MAPK/ERK Pathway
  3. MAP4K
  4. PF-06260933 hydrochloride

PF-06260933 hydrochloride 是 PF-06260933 (HY-19562) 的盐酸盐形式。PF-06260933 hydrochloride 是一种具有口服活性的，高度选择性的 MAP4K4 小分子抑制剂，在激酶实验和细胞实验中的 IC50 值分别为 3.7 和 160 nM。

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PF-06260933 hydrochloride Chemical Structure

PF-06260933 hydrochloride Chemical Structure

CAS No. : 1883548-86-4

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PF-06260933 hydrochloride 的其他形式现货产品:

Other Forms of PF-06260933 hydrochloride:

PF-06260933 hydrochloride 相关抗体

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查看 MAP4K 亚型特异性产品:

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MAP4K2/GCK MAP4K3/GLK MAP4K4/HGK MAP4K5/KHS1 MAP4K6/MINK1 MAP4K7/TNIK MAP4K1/HPK1

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

PF-06260933 hydrochloride is the hydrochloride form of PF-06260933 (HY-19562). PF-06260933 hydrochloride is an orally active and highly selective inhibitor of MAP4K4 with IC50s of 3.7 and 160 nM for kinase and cell, respectively[1].

分子量

369.68

Formula

C16H15Cl3N4
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

PF-06260933 hydrochloride 相关分类

  • 摩尔计算器

  • 稀释计算器

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PF-062609331883548-86-4PF06260933PF 06260933MAP4KMAPK Kinase Kinase KinasehydrochlorideMAP4K4 inhibitororally activekinaseInhibitorinhibitorinhibit

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产品名称：
PF-06260933 hydrochloride
目录号：
HY-19562A
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