2. 天然产物
  3. 植物 甾体类
  4. 茄科
  5. 苦蘵
  6. Physagulide J

Physagulide J 是一种睡茄内酯类化合物，能够从苦蘵 (Physalis angulata L.) 中分离得到。苦蘵的多种活性成分表现出抗炎及抗肿瘤活性。

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Physagulide J Chemical Structure

Physagulide J Chemical Structure

CAS No. : 1496524-09-4

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Physagulide J 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Physagulide J is a kind of withanolides compound that can be isolated from Physalis angulata L.. Many kinds of active ingredients of Physalis angulata L. shows anti-inflammatory and anti-tumor activity[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
786-0 IC50
0.39 μM
Compound: 17
Antiproliferative activity against human 786-0 cells assessed as inhibition of cell viability after 48 hrs by MTT reduction assay
Antiproliferative activity against human 786-0 cells assessed as inhibition of cell viability after 48 hrs by MTT reduction assay
[PMID: 27295506]
A498 IC50
0.71 μM
Compound: 17
Antiproliferative activity against human A498 cells assessed as inhibition of cell viability after 48 hrs by MTT reduction assay
Antiproliferative activity against human A498 cells assessed as inhibition of cell viability after 48 hrs by MTT reduction assay
[PMID: 27295506]
ACHN IC50
0.73 μM
Compound: 17
Antiproliferative activity against human ACHN cells assessed as inhibition of cell viability after 48 hrs by MTT reduction assay
Antiproliferative activity against human ACHN cells assessed as inhibition of cell viability after 48 hrs by MTT reduction assay
[PMID: 27295506]
CWR22R IC50
0.9 μM
Compound: 17
Antiproliferative activity against human 22Rv1 cells assessed as inhibition of cell viability after 48 hrs by MTT reduction assay
Antiproliferative activity against human 22Rv1 cells assessed as inhibition of cell viability after 48 hrs by MTT reduction assay
[PMID: 27295506]
LNCaP C4-2B IC50
0.49 μM
Compound: 17
Antiproliferative activity against human C4-2B cells assessed as inhibition of cell viability after 48 hrs by MTT reduction assay
Antiproliferative activity against human C4-2B cells assessed as inhibition of cell viability after 48 hrs by MTT reduction assay
[PMID: 27295506]
RAW264.7 IC50
1.36 μM
Compound: 17
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs by Griess assay
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs by Griess assay
[PMID: 27295506]
分子量

512.63

Formula

C30H40O7
CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Physagulide J 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Physagulide J1496524-09-4OthersInhibitorinhibitorinhibit

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Physagulide J
目录号：
HY-N11008
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