2. Anti-infection
  3. Antibiotic
  4. Pibrozelesin

Pibrozelesin  (Synonyms: KW 2189 free base)

目录号: HY-19137
产品使用指南

摩尔计算器

Pibrozelesin (KW 2189 free base) 是抗生素 Duocarmycin B2 的衍生物。Pibrozelesin 具有抗肿瘤活性，可抑制细胞 H69 的增殖，IC50 为 1.9 μM。Pibrozelesin 被羧基酯酶 (carboxyl esterase) 激活后可诱导 DNA 链断裂。

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Pibrozelesin Chemical Structure

Pibrozelesin Chemical Structure

CAS No. : 154889-68-6

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Pibrozelesin 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Pibrozelesin (KW 2189 free base) is the derivative of antibiotic Duocarmycin B2. Pibrozelesin exhibits antitumor activity, inhibits proliferation of cell H69 with an IC50 of 1.9 μM. Pibrozelesin induces the DNA strand breaks upon activation via carboxyl esterase[1].

分子量

698.56

Formula

C32H36BrN5O8
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Pibrozelesin 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Pibrozelesin154889-68-6KW 2189KW2189KW-2189AntibioticNCI-H29H69antibioticantitumorInhibitorinhibitorinhibit

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