1. Epigenetics
  2. MicroRNA
  3. PIN1 inhibitor 2

PIN1 inhibitor 2 (compound 12) 是一种有效的 PIN1 抑制剂。PIN1 inhibitor 2 显示出抗肿瘤活性,对 MCF7 细胞的 IC50 为 9.55 µM。PIN1 inhibitor 2 具有研究乳腺癌的潜力。

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PIN1 inhibitor 2 Chemical Structure

PIN1 inhibitor 2 Chemical Structure

CAS No. : 2417101-28-9

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

PIN1 inhibitor 2 (compound 12) is a potent PIN1 inhibitor. PIN1 inhibitor 2 shows antitumor activity with an IC50 of 9.55 µM for MCF7 cells. PIN1 inhibitor 2 has the potential for the research of breast cancer[1].

IC50 & Target

PIN1[1]

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
MCF7 IC50
9.55 μM
Compound: 12
Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 24 hrs by MTT assay
Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 24 hrs by MTT assay
[PMID: 32307260]
分子量

319.49

Formula

C16H21N3S2

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • 稀释计算器

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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PIN1 inhibitor 2
目录号:
HY-147710
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