2. GPCR/G Protein
  3. Platelet-activating Factor Receptor (PAFR)
  4. Pinusolidic acid

Pinusolidic Acid 是一种血小板激活因子 (PAF) 抑制剂，IC50 为 23 μM。

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Pinusolidic acid Chemical Structure

Pinusolidic acid Chemical Structure

CAS No. : 40433-82-7

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Pinusolidic acid 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Pinusolidic acid is a platelet-activating factor (PAF) inhibitor with an IC50 of 23 μM[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
A549 IC50
> 40 μM
Compound: 21
Cytotoxicity against human A549 cells after 48 hrs by MTT assay
Cytotoxicity against human A549 cells after 48 hrs by MTT assay
[PMID: 23691952]
HL-60 IC50
> 40 μM
Compound: 21
Cytotoxicity against human HL60 cells after 48 hrs by MTT assay
Cytotoxicity against human HL60 cells after 48 hrs by MTT assay
[PMID: 23691952]
MCF7 IC50
> 40 μM
Compound: 21
Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
[PMID: 23691952]
SMMC-7721 IC50
> 40 μM
Compound: 21
Cytotoxicity against human SMMC7721 cells after 48 hrs by MTT assay
Cytotoxicity against human SMMC7721 cells after 48 hrs by MTT assay
[PMID: 23691952]
SW480 IC50
> 40 μM
Compound: 21
Cytotoxicity against human SW480 cells after 48 hrs by MTT assay
Cytotoxicity against human SW480 cells after 48 hrs by MTT assay
[PMID: 23691952]
Vero CC50
> 750 μM
Compound: 9
Cytotoxicity against Vero E6 cells by MTT assay
Cytotoxicity against Vero E6 cells by MTT assay
[PMID: 17663539]
Vero EC50
4.71 μM
Compound: 9
Antiviral activity against SARS coronavirus in Vero E6 cells assessed as inhibition of viral replication by ELISA
Antiviral activity against SARS coronavirus in Vero E6 cells assessed as inhibition of viral replication by ELISA
[PMID: 17663539]
分子量

332.43

Formula

C20H28O4
CAS 号
结构分类
初始来源

Antrodia camphorata
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Pinusolidic acid 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Pinusolidic acid40433-82-7Platelet-activating Factor Receptor (PAFR)Inhibitorinhibitorinhibit

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