2. Immunology/Inflammation Apoptosis
  3. PD-1/PD-L1 Apoptosis
  4. PL120131

PL120131 是一种 PD-1/PD-L1 抑制肽, 可以通过与 PD-1 结合来干扰 PD-1/PD-L1 的相互作用。PL120131 能够抑制 PD-1 介导的凋亡信号通路，使 Jurkat 细胞和原发性淋巴细胞免于凋亡 (apoptosis)。PL120131 有助于细胞毒性 T 淋巴细胞 (CTL) 发挥抗肿瘤活性。

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Custom Peptide Synthesis

PL120131 Chemical Structure

PL120131 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
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100 mg   询价  
250 mg   询价  

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Customer Review

PL120131 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

PL120131 is a PD-1/PD-L1 inhibitory peptide that can interfere with the interaction of PD-1/PD-L1 by binding to PD-1. PL120131 is capable of inhibiting the PD-1-mediated apoptotic signaling pathway, protecting Jurkat cells and primary lymphocytes from apoptosis. PL120131 aids in the antitumor activity of cytotoxic T lymphocytes (CTLs)[1].

分子量

1404.61

Formula

C62H105N19O18
Sequence

Ac-Gly-Ala-Asp-Tyr-Lys-Arg-Ile-Thr-Val-Lys-Val-Asn-NH2
Sequence Shortening

Ac-GADYKRITVKVN-NH2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

PL120131 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PL120131PL 120131PL-120131PD-1/PD-L1ApoptosisPD-1/Programmed death-ligand 1cytotoxic T lymphocyte (CTL)apoptosisantibody based immunotherapiesJurkat cellsprimary lymphocytesantitumor activityInhibitorinhibitorinhibit

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产品名称：
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目录号：
HY-P10838
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