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  6. (+)-Epipinoresinol

(+)-Epipinoresinol  (Synonyms: (+)-表松脂酚；(+)-表松脂素)

目录号: HY-N7534 纯度: 98.12%
COA 产品使用指南 技术支持

(+)-Epipinoresinol 是木脂素类化合物。CYP81Q3 特异性催化 (+)-Epipinoresinol 中的亚甲二氧基桥（MDB）生成，从而产生 (+)-Pluviatilol。

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(+)-Epipinoresinol Chemical Structure

(+)-Epipinoresinol Chemical Structure

CAS No. : 24404-50-0

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规格 价格 是否有货
1 mg ￥2800
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5 mg 现货 询问价格 & 货期

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Other Forms of (+)-Epipinoresinol:

(+)-Epipinoresinol 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

(+)-Epipinoresinol is a lignan compound. CYP81Q3 specifically catalyzes methylenedioxy bridge (MDB) formation in (+)-Epipinoresinol to produce (+)-Pluviatilol[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
HepG2 EC50
> 60 μM
Compound: 3
Transactivation of GAL4-fused PPARalpha LBD expressed in HepG2 cells after 20 hrs by luminescence assay
Transactivation of GAL4-fused PPARalpha LBD expressed in HepG2 cells after 20 hrs by luminescence assay
[PMID: 22381047]
HepG2 EC50
10.3 μM
Compound: 3
Transactivation of PPAR expressed in HepG2 cells after 20 hrs by luminescence assay
Transactivation of PPAR expressed in HepG2 cells after 20 hrs by luminescence assay
[PMID: 22381047]
HepG2 EC50
49.5 μM
Compound: 3
Transactivation of GAL4-fused PPARbeta LBD expressed in HepG2 cells after 20 hrs by luminescence assay
Transactivation of GAL4-fused PPARbeta LBD expressed in HepG2 cells after 20 hrs by luminescence assay
[PMID: 22381047]
HepG2 EC50
58.6 μM
Compound: 3
Transactivation of GAL4-fused PPARgamma LBD expressed in HepG2 cells after 20 hrs by luminescence assay
Transactivation of GAL4-fused PPARgamma LBD expressed in HepG2 cells after 20 hrs by luminescence assay
[PMID: 22381047]
Neutrophil IC50
> 10 μg/mL
Compound: 18
Anti-inflammatory activity in human neutrophils assessed as inhibition of fMLP/CB-induced elastase release pre-incubated for 5 mins before fMLP/CB stimulation using MeO-Suc-Ala-Ala-Pro-Val-pnitroanilide as substrate
Anti-inflammatory activity in human neutrophils assessed as inhibition of fMLP/CB-induced elastase release pre-incubated for 5 mins before fMLP/CB stimulation using MeO-Suc-Ala-Ala-Pro-Val-pnitroanilide as substrate
[PMID: 28218000]
Neutrophil IC50
3.4 μg/mL
Compound: 18
Anti-inflammatory activity in human neutrophils assessed as inhibition of fMLP/CB-induced superoxide anion generation by measuring superoxide dismutase SOD-inhibitable ferricytochrome c reduction incubated for 5 mins before fMLP/CB stimulation for 3 mins
Anti-inflammatory activity in human neutrophils assessed as inhibition of fMLP/CB-induced superoxide anion generation by measuring superoxide dismutase SOD-inhibitable ferricytochrome c reduction incubated for 5 mins before fMLP/CB stimulation for 3 mins
[PMID: 28218000]
RAW264.7 IC50
> 50 μM
Compound: 15
Inhibition of LPS-induced IL-1beta production in mouse RAW264.7 cells after 24 hrs by ELISA
Inhibition of LPS-induced IL-1beta production in mouse RAW264.7 cells after 24 hrs by ELISA
[PMID: 24963714]
RAW264.7 IC50
39.5 μM
Compound: 15
Inhibition of LPS-induced NO production in mouse RAW264.7 cells after 24 hrs by Griess reagent based assay
Inhibition of LPS-induced NO production in mouse RAW264.7 cells after 24 hrs by Griess reagent based assay
[PMID: 24963714]
分子量

358.39

Formula

C20H22O6
CAS 号
性状

固体

颜色

White to off-white

中文名称

(+)-表松脂酚；(+)-表松脂素
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

纯度 & 产品资料
参考文献

(+)-Epipinoresinol 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(+)-Epipinoresinol24404-50-0(+)-表松脂酚(+)-表松脂素OthersInhibitorinhibitorinhibit

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