2. PROTAC
  3. E3 Ligase Ligand-Linker Conjugates
  4. Pomalidomide-C4-NH2 hydrochloride

Pomalidomide-C4-NH2 hydrochloride 

目录号: HY-138845A
COA 产品使用指南

摩尔计算器

Pomalidomide-C4-NH2 hydrochloride 是一种合成的 E3 连接酶配体-linker 偶联物，包含基于 Pomalidomide 的 cereblon 配体和 1 个 linker，可用于合成 PROTAC。

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Pomalidomide-C4-NH2 hydrochloride Chemical Structure

Pomalidomide-C4-NH2 hydrochloride Chemical Structure

CAS No. : 2162120-73-0

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Other Forms of Pomalidomide-C4-NH2 hydrochloride:

Pomalidomide-C4-NH2 hydrochloride 相关抗体

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查看 E3 Ligase Ligand-Linker Conjugates 亚型特异性产品:

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von Hippel-Lindau (VHL) MDM2 Cereblon cIAP1 Aryl Hydrocarbon Receptor

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Pomalidomide-C4-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology[1].

IC50 & Target

Cereblon

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Pomalidomide-C4-NH2 hydrochloride 相关抗体:
分子量

380.83

Formula

C17H21ClN4O4
CAS 号
性状

固体

颜色

Light yellow to yellow

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

-20°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

纯度 & 产品资料
参考文献

Pomalidomide-C4-NH2 hydrochloride 相关分类

  • 摩尔计算器

  • 稀释计算器

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  • Do most proteins show cross-species activity?

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Keywords:

Pomalidomide-C4-NH22162120-73-0E3 Ligase Ligand-Linker ConjugatesInhibitorinhibitorinhibit

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目录号：
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