1. GPCR/G Protein
  2. GLP Receptor
  3. PP18

PP18 是一种基于 OXM 的新型双 GLP-1 和胰高血糖素受体激动剂,对 hGLP-1R 的EC50 值为 0.487 nM;对 hGcgR 的EC50 值为 0.188 nM。

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Custom Peptide Synthesis

PP18 Chemical Structure

PP18 Chemical Structure

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     可免费申领三个不同产品的试用装。

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规格 是否有货
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Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

PP18 is a novel OXM-based dual GLP-1 and glucagon receptor agonist with EC50 values of 0.487 nM target hGLP-1R and 0.188 nM target hGcgR[1].

分子量

6168.83

Formula

C269H426N74O88S2

Sequence

Ala-Cys-Ala-Glu-Leu-Val-Asp-Asn-Ala-Val-Ala-Ile-Gly-Gly-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys(AEEA-AEEA-γGlu-C18 diacid)-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr-Ala-Arg-Asn-Arg-Asn-Asn-Ile-Ala

Sequence Shortening

ACAELVDNAVAIGGQGTFTSDYS-K(AEEA-AEEA-γGlu-C18 diacid)-YLDSRRAQDFVQWLMNTARNRNNIA

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

产品名称:
PP18
目录号:
HY-P10327
需求量: