2. GPCR/G Protein Membrane Transporter/Ion Channel Neuronal Signaling Metabolic Enzyme/Protease Autophagy
  3. Cannabinoid Receptor TRP Channel Endogenous Metabolite Autophagy
  4. Pregnenolone monosulfate sodium-13C2,d2

Pregnenolone monosulfate sodium-13C2,d2  (Synonyms: 3β-Hydroxy-5-pregnen-20-one monosulfate (sodium)-13C2,d2)

目录号: HY-110189S
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摩尔计算器

Pregnenolone monosulfate (sodium)-13C2,d2 是一种 13C- 和氘代标记的 Pregnenolone monosulfate (sodium salt)。Pregnenolone monosulfate sodium salt (3β-Hydroxy-5-pregnen-20-one monosulfate sodium salt) 是一种功能强大的神经甾体，是包括甾体酮在内的各种甾体激素的主要前体。Pregnenolone monosulfate sodium salt 是大麻素 CB1 受体的信号传导特异性抑制剂，抑制由 CB1 受体介导的四氢大麻酚 (THC) 的作用。Pregnenolone monosulfate sodium salt 可以保护大脑免受大麻毒性的侵袭。Pregnenolone monosulfate sodium salt 也是一种 TRPM3 通道激活剂，也可以弱激活 TRPM1 通道。

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Pregnenolone monosulfate sodium-<sup>13</sup>C<sub>2</sub>,d<sub>2</sub> Chemical Structure

Pregnenolone monosulfate sodium-13C2,d2 Chemical Structure

CAS No. : 2483824-22-0

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Other Forms of Pregnenolone monosulfate sodium-13C2,d2:

Pregnenolone monosulfate sodium-13C2,d2 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Pregnenolone monosulfate (sodium)-13C2,d2 is the 13C- and deuterium labeled Pregnenolone monosulfate sodium. Pregnenolone monosulfate sodium (3β-Hydroxy-5-pregnen-20-one monosulfate sodium) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone monosulfate sodium salt acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone monosulfate sodium salt can protect the brain from cannabis intoxication[1][2]. Pregnenolone monosulfate sodium salt is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels[3].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Pregnenolone monosulfate sodium-13C2,d2 相关抗体:
分子量

422.52

Formula

C1913C2H29D2NaO5S
CAS 号
非标记 CAS

1852-38-6
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Pregnenolone monosulfate sodium-13C2,d2 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Pregnenolone monosulfate sodium-13C2,d22483824-22-03β-Hydroxy-5-pregnen-20-one monosulfate sodium-13C2,d2Cannabinoid ReceptorTRP ChannelEndogenous MetaboliteAutophagyTransient receptor potential channelsInhibitorinhibitorinhibit

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