1. Metabolic Enzyme/Protease
  2. Heme oxygenase (HO)
  3. Probucol dithiobisphenol

Probucol dithiobisphenol  (Synonyms: DTBP)

目录号: HY-W424839
产品使用指南 技术支持

Probucol dithiobisphenol (DTBP) 是 Probucol (HY-B0388) 的衍生物。Probucol dithiobisphenol 诱导血红素加氧酶 1 (HO-1) 的产生,并表现出抗氧化活性。Probucol dithiobisphenol 在 ApoE−/− 小鼠模型中抑制主动脉的动脉粥样硬化病变,在兔动脉损伤模型中促进动脉再内皮化并抑制再狭窄。Probucol dithiobisphenol 具有口服活性。

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Probucol dithiobisphenol Chemical Structure

Probucol dithiobisphenol Chemical Structure

CAS No. : 6386-58-9

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Probucol dithiobisphenol (DTBP) is the derivative of Probucol (HY-B0388). Probucol dithiobisphenol induces the production of heme oxygenase 1 (HO-1), and exhibits antioxidant activity. Probucol dithiobisphenol inhibits atherosclerotic lesions in ApoE−/− mice aorta, promotes re-endothelialization of aorta and inhibits restenosis in rabbit arterial injury models. Probucol dithiobisphenol is orally active[1].

分子量

474.76

Formula

C28H42O2S2

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • 稀释计算器

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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