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  4. Progranulin modulator-3

Progranulin modulator-3 (compd C40) 是一种可穿透血脑屏障和具有口服活性的颗粒蛋白前体 (PGRN) 诱导剂。Progranulin modulator-3 可用于神经学研究。

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Progranulin modulator-3 Chemical Structure

Progranulin modulator-3 Chemical Structure

CAS No. : 371116-39-1

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Progranulin modulator-3 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Progranulin modulator-3 (compd C40) is a brain-penetrant and orally active progranulin (PGRN) inducer. Progranulin modulator-3 can be used for neurological research[1].

体外研究
(In Vitro)

Progranulin modulator-3 (1-30 μM, 48 h) 剂量依赖性地诱导 N2A 细胞产生 PGRN 蛋白[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Progranulin modulator-3 相关抗体:
体内研究
(In Vivo)

Progranulin modulator-3 (10 mg/kg, 腹腔注射，24 小时) 在小鼠血浆和脑中的半衰期为 41 分钟，Cmax 分别为 1498 ng/mL 和 6246 ng/g，并增加 Grn+/− 小鼠脑中的 PGRN 蛋白水平[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

304.30

Formula

C18H12N2O3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Progranulin modulator-3 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Progranulin modulator-3371116-39-1Progranulin modulator3Progranulin modulator 3Othersbrain-penetrantorally activePGRNneurologicalN2AGrn+/? mouseInhibitorinhibitorinhibit

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目录号：
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