2. 多肽产品
  3. 多肽及其衍生物
  4. 抑制剂与底物肽
  5. Properdistatin

Properdistatin 是一种来源于备解素的血小板反应蛋白 1 (TSP-1) 结构域的肽。Properdistatin 抑制血管生成并改善血管功能。Properdistatin 具有用于黑色素瘤研究的潜力。

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Custom Peptide Synthesis

Properdistatin Chemical Structure

Properdistatin Chemical Structure

CAS No. : 945373-85-3

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Properdistatin 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Properdistatin is a peptide derived from the thrombospondin 1 (TSP-1) domain of properdin. Properdistatin inhibits angiogenesis and improves vascular function. Properdistatin has the potential for the research of melanoma[1].

体内研究
(In Vivo)

Properdistatin (80 mg/kg; 腹腔注射; 每日一次, 持续 4 天) 抑制小鼠黑色素瘤异种移植模型的血管生成并改善血管功能[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Adult female BALB/c nu/nu mice (R-18, A-07, and D-12 human melanoma cells)[1]
Dosage: 80 mg/kg
Administration: I.p.; daily for 4 days
Result: Inhibited angiogenesis in human melanoma xenografts with low TSP-1 expression, selectively removed small-diameter capillaries, but did not change the morphology of tumor arterioles or tumor venules, and reduced blood supply times and increased plasma velocities.
分子量

2177.47

Formula

C89H149N33O27S2
CAS 号
Sequence Shortening

GPWEPCSVTCSKGTRTRRR
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Properdistatin 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Properdistatin945373-85-3OthersangiogenesisTSP-1melanomaR-18A-07D-12 cellsInhibitorinhibitorinhibit

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