1. Anti-infection
  2. Antibiotic
  3. Propionylmaridomycin

Propionylmaridomycin是一种大环内酯抗生素,具有抗菌活性。Propionylmaridomycin在胃肠道中迅速吸收,并能迅速分布到组织中。Propionylmaridomycin在肝脏、肾脏和肺部的放射性水平明显高于血浆,而在脑部的分布较少。Propionylmaridomycin的排泄主要通过粪便进行,且高粪便回收率是由于未被吸收的化合物和胆汁排泄的化合物及其代谢物造成的。Propionylmaridomycin在肺部表现出最高的抗菌活性。Propionylmaridomycin在大鼠体内被完全转化为几种代谢物,其中4''-去丙酰基-9-丙酰基maridomycin被鉴定为主要代谢物。

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Propionylmaridomycin Chemical Structure

Propionylmaridomycin Chemical Structure

CAS No. : 35775-65-6

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Propionylmaridomycin is a macrolide antibiotic with antibacterial activity. Propionylmaridomycin is rapidly absorbed from the gastrointestinal tract and rapidly distributed to tissues. Propionylmaridomycin radioactivity levels in the liver, kidneys, and lungs were significantly higher than in plasma, while distribution to the brain was less. Propionylmaridomycin is excreted primarily through the feces, and the high fecal recovery rate is due to unabsorbed compounds and biliary excretion of compounds and their metabolites. Propionylmaridomycin exhibits the highest antibacterial activity in the lungs. Propionylmaridomycin is completely converted to several metabolites in rats, of which 4''-depropionyl-9-propionylmaridomycin was identified as the major metabolite[1].

分子量

914.08

Formula

C46H75NO17

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

Propionylmaridomycin 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Propionylmaridomycin
目录号:
HY-137263
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