2. PROTAC Apoptosis
  3. PROTACs Apoptosis
  4. PROTAC TRIB2 degrader-1

PROTAC TRIB2 degrader-1 (Compound 5k) 是一种有效的 TRIB2 降解剂，通过 CRBN 依赖的泛素-蛋白酶体途径选择性的诱导 TRIB2 降解。PROTAC TRIB2 degrader-1 能抑制细胞增殖和诱导细胞凋亡(apoptosis)，可以用于癌症的研究。(靶蛋白配体 (PINK): HY-168275; linker (black): HY-168276; E3 连接酶配体与连接子的缀合物: HY-168277; E3 连接酶 (Blue):HY-W023573)。

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PROTAC TRIB2 degrader-1 Chemical Structure

PROTAC TRIB2 degrader-1 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

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PROTAC TRIB2 degrader-1 相关抗体

Top Publications Citing Use of Products

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von Hippel-Lindau (VHL) Cereblon MDM2 cIAP1

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

PROTAC TRIB2 degrader-1 (Compound 5k) is an effective TRIB2 degrader that selectively induces TRIB2 degradation through the CRBN-dependent ubiquitin-proteasome pathway. PROTAC TRIB2 degrader-1 can inhibit cell proliferation and induce cell apoptosis, and can be used in cancer research. (Target protein ligand (Pink): HY-168275; linker (black): HY-168276; E3 Ligase Ligand-Linker Conjugates: HY-168277; E3 ligase (Blue): HY-W023573)[1].

分子量

812.89

Formula

C45H45FN8O6
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

PROTAC TRIB2 degrader-1 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PROTAC TRIB2 degrader-1PROTACsApoptosisPC3 cell linesCancerInhibitorinhibitorinhibit

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产品名称：
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目录号：
HY-168274
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