荧光原位杂交 (FISH) 是一种分子生物学技术，用于在细胞或组织中定位特定核酸序列。通过使用荧光标记的核酸探针，FISH 允许研究者直接可视化和定位 DNA 或 RNA。该技术在染色体分析、基因定位、细胞核型分析等领域广泛应用。FISH 不仅提供高空间分辨率，还允许多目标同时检测，使其成为生物医学研究、临床诊断和癌症研究中的强大工具。

Fluorescence in situ hybridization (FISH) is a molecular biology technique used to locate specific nucleic acid sequences in cells or tissues. By using fluorescently labeled nucleic acid probes, FISH allows researchers to directly visualize and localize DNA or RNA. This technology is widely used in chromosome analysis, gene mapping, karyotype analysis and other fields. FISH not only provides high spatial resolution but also allows for simultaneous detection of multiple targets, making it a powerful tool in biomedical research, clinical diagnostics, and cancer research.