1. GPCR/G Protein Neuronal Signaling Immunology/Inflammation
  2. Histamine Receptor
  3. Proxyfan Oxalate

Proxyfan Oxalate 是一种有效的组胺 H3 受体 (histamine H3 receptor) 拮抗剂,对大鼠和人类 H3 受体的 Ki 值分别为 2.9 nM 和 2.7 nM。Proxyfan Oxalate 对 H3 受体的抑制作用比其他组胺受体的抑制作用高 1000 多倍。

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Proxyfan Oxalate Chemical Structure

Proxyfan Oxalate Chemical Structure

CAS No. : 1620017-81-3

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Proxyfan Oxalate is a potent histamine H3 receptor antagonist with Ki values of 2.9 nM and 2.7 nM for rat and human H3 receptor, respectively. Proxyfan Oxalate is over 1000-fold more potent at H3 receptors than other histamine receptors[1][2].

IC50 & Target[1]

Rat H3LR

2.9 nM (Ki)

Human H3LR

2.7 nM (Ki)

分子量

306.31

Formula

C15H18N2O5

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • 稀释计算器

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Proxyfan Oxalate
目录号:
HY-107557A
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