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QPy-TPA 是一种脂质探针,在光照射下可诱导 B16 和 HepG2 细胞中的非铁死亡和脂质动态调节。 QPy-TPA 的最大吸收波长为 400 nm,最大发射波长为 590 nm。

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QPy-TPA Chemical Structure

QPy-TPA Chemical Structure

CAS No. : 2738332-94-8

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  • 生物活性

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生物活性

QPy-TPA is a lipopjilc probes, which induces non-ferroptotic cell death and lipid dynamic regularion in B16 and HepG2 cells upon light irradiation. QPy-TPA reveals a maximum absorption wavelength of 400 nm and a maximum emission wavelength of 590 nm[1].

体外研究
(In Vitro)

QPy-TPA (5 μM) 在细胞 B16 和 HepG2 中表现出光细胞毒性,而 QPy-TPA (50 μM) 在没有光照射的情况下在 B16 和 HepG2 中表现出 >50% 的存活率[1]
QPy-TPA 在光照射条件下上调氧化脂质,尤其是 PC 和 PE[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Cytotoxicity Assay[1]

Cell Line: B16, HepG2
Concentration: 0-50 μM
Incubation Time: 48 h
Result: Exhibited survival rate >50% without light irradiation, decreased cell viabilities in B16 and HepG2 upon light irradiation, which is irreversible by Fer-1.
分子量

492.57

Formula

C33H24N4O

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
QPy-TPA
目录号:
HY-163287
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