2. Metabolic Enzyme/Protease
  3. Amylases
  4. Quercetin 3-(6″-caffeoylsophoroside)

Quercetin 3-(6″-caffeoylsophoroside) 

目录号: HY-N11844
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Quercetin 3-(6″-caffeoylsophoroside) 是一种具有口服活性的 α-淀粉酶抑制剂，对 α- 淀粉酶的 IC50 为 73.66 μg/mL。Quercetin 3-(6″-caffeoylsophoroside) 存在于碎米荠的水合甲醇提取物中，能通过减少氧化应激和抑制 α- 淀粉酶发挥抗糖尿病活性。Quercetin 3-(6″-caffeoylsophoroside) 可用于糖尿病研究。

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Quercetin 3-(6″-caffeoylsophoroside) Chemical Structure

Quercetin 3-(6″-caffeoylsophoroside) Chemical Structure

CAS No. : 1032595-77-9

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Quercetin 3-(6″-caffeoylsophoroside) 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Quercetin 3-(6″-caffeoylsophoroside) is an orally active α-amylase inhibitor, with an IC50 of 73.66 μg/mL. Quercetin 3-(6″-caffeoylsophoroside) presents in thehydro-methanolic extract of Cardamine hirsuta Linn. Quercetin 3-(6″-caffeoylsophoroside) shows the antidiabetic activities by oxidative stress reduction and α-amylase inhibition. Quercetin 3-(6″-caffeoylsophoroside) can be used for diabetes mellitus research[1].

体内研究
(In Vivo)

Quercetin 3-(6″-caffeoylsophoroside) (50，100，500，1000，2000 mg/kg，口服灌胃) 在 SD 大鼠急性口服毒性试验中显示安全性，可用于抗糖尿病研究[1]。
Quercetin 3-(6″-caffeoylsophoroside) (125，250，500 mg/kg，口服灌胃) 通过减少氧化应激和抑制 α-淀粉酶改善了 SD 大鼠的 2 型糖尿病[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: FED HFD (45% fat) for 30 days to induce type 2 diabetes mellitus in SD rats[1]
Dosage: 125, 250, 500 mg/kg
Administration: Oral gavage (p.o.)
Result: Significantly decreased the blood glucose level, improved biochemical parameters as well as oxidative stress by reduction of lipid peroxidation, and increased high-density lipoproteins with dose of 500mg/kg.
Enhanced activities of glutathione-s-transferase, glutathione, superoxide dismutase.
Restored cellular architecture in the histopathological examination.
Animal Model: Acute oral toxicity in 8-week male SD rats[1]
Dosage: 50, 100, 500, 1000, and 2000 mg/kg
Administration: Oral gavage (p.o.)
Result: Safe for use in anti-diabetic research.
分子量

532.63

Formula

C27H40N4O7
CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Quercetin 3-(6″-caffeoylsophoroside) 相关分类

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Keywords:

Quercetin 3-(6″-caffeoylsophoroside)1032595-77-9AmylasesAntidiabetic AgentDiabetes mellitus (T2DM)α-amylase inhibitoroxidative stressInhibitorinhibitorinhibit

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