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  4. (R)-KMH-233

(R)-KMH-233 是 KMH-233 (HY-120139) 的异构体，可作为实验中的对照化合物。KMH-233 是一种有效，可逆的且选择性的 l 型氨基酸转运蛋白 1 (LAT1) 抑制剂，可抑制LAT1底物，l-leucin 的摄取 (IC50=18 μM) 以及细胞生长。即使在低浓度 (25 μM) 下，KMH-233 仍可显着增强 Bestatin 和顺铂的疗效。

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(R)-KMH-233 Chemical Structure

(R)-KMH-233 Chemical Structure

CAS No. : 2994330-89-9

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规格 价格 是否有货
1 mg ￥1100
询问价格 & 货期
5 mg ￥3100
询问价格 & 货期
10 mg ￥4900
询问价格 & 货期
25 mg 现货 询问价格 & 货期

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Other Forms of (R)-KMH-233:

(R)-KMH-233 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

(R)-KMH-233 is the isomer of KMH-233 (HY-120139), and can be used as an experimental control. KMH-233, a potent, reversible and selective l-type amino acid transporter 1 (LAT1) inhibitor, inhibits the uptake of LAT1 substrate, l-leucin (IC50=18 μM) as well as cell growth. KMH-233 significantly potentiates the efficacy of Bestatin and Cisplatin even at low concentrations (25 μM)[1].

分子量

587.58

Formula

C32H25N7O5
CAS 号
性状

固体

颜色

Light yellow to yellow

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料
参考文献

(R)-KMH-233 相关分类

  • 摩尔计算器

  • 稀释计算器

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(R)-KMH-2332994330-89-9OtherstransportaminoacidsgrowthcancercellsMCF-7Inhibitorinhibitorinhibit

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目录号：
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