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  3. (R,R,S)-GAT107

(R,R,S)-GAT107是一种α7烟碱受体的全激动正调节剂,具有显著的生物活性。它的活性完全存在于其(+)-异构体1b中,而(-)-异构体1a在共同应用时并不影响其活性。研究表明,(R,R,S)-GAT107是目前已知的最有效的α7烟碱受体的ago-PAM,具有进一步在体内评估的潜力。

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(R,R,S)-GAT107 Chemical Structure

(R,R,S)-GAT107 Chemical Structure

CAS No. : 1426240-47-2

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

(R,R,S)-GAT107 is a fully agonistic positive modulator of α7 nicotinic receptors with significant biological activity. Its activity is entirely present in its (+)-isomer 1b, while (-)-isomer 1a does not affect its activity when used together. Studies have shown that (R,R,S)-GAT107 is the most potent ago-PAM for α7 nicotinic receptors currently known and has the potential for further in vivo evaluation[1].

分子量

405.31

Formula

C18H17BrN2O2S

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

(R,R,S)-GAT107 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
(R,R,S)-GAT107
目录号:
HY-167922
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