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(Rac)-Telinavir  (Synonyms: (Rac)-SC-52151)

目录号: HY-106395A
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(Rac)-Telinavir ((Rac)-SC-52151) 是一种强效、选择性、紧密结合的人类免疫缺陷病毒 (HIV) 蛋白酶抑制剂，具有显著的抗 HIV 活性。(Rac)-Telinavir 对各种 HIV 毒株（包括 HIV-1、HIV-2 和猿猴免疫缺陷病毒）的平均 50% 有效浓度为 26 ng/ml (43 nM)。(Rac)-Telinavir 与核苷逆转录酶抑制剂联合使用，在抑制 HIV-1 复制方面具有协同作用，且不会产生附加毒性。(Rac)-Telinavir 在人血浆中与蛋白质结合率高，在红细胞中的分配率低。

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(Rac)-Telinavir Chemical Structure

(Rac)-Telinavir Chemical Structure

CAS No. : 162679-88-1

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生物活性

(Rac)-Telinavir ((Rac)-SC-52151) is a potent, selective, tight-binding human immunodeficiency virus (HIV) protease inhibitor that exhibits significant anti-HIV activity. (Rac)-Telinavir has a mean 50% effective concentration of 26 ng/ml (43 nM) against various strains of HIV, including HIV-1, HIV-2, and simian immunodeficiency virus. (Rac)-Telinavir, in combination with nucleoside reverse transcriptase inhibitors, demonstrates synergistic effects on inhibiting HIV-1 replication without additive toxicity. (Rac)-Telinavir is highly protein bound in human plasma and exhibits low partitioning into erythrocytes.

分子量

604.74

Formula

C33H44N6O5
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

(Rac)-Telinavir 相关分类

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Keywords:

(Rac)-Telinavir162679-88-1(Rac)-SC-52151OthersInhibitorinhibitorinhibit

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