2. Cell Cycle/DNA Damage
  3. DNA/RNA Synthesis
  4. (±)2-(14,15-Epoxyeicosatrienoyl) glycerol

(±)2-(14,15-Epoxyeicosatrienoyl) glycerol  (Synonyms: (±)2-14,15-EG)

目录号: HY-165060
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(±)2-(14,15-Epoxyeicosatrienoyl) glycerol ((±)2-14,15-EG) 是肾脏中 2-Arachidonoyl glycerol (2-AG) 的新型 CYP450 代谢物。7 (±)2-14,15-EG 是一种有效的对肾上皮细胞具有促丝裂原作用，可增加 LLCPKcl4 细胞中的 DNA 合成。(±)2-(14,15-Epoxyeicosatrienoyl) glycerol 可激活金属蛋白酶 ADAM17，从而启动 EGFR-ERK 信号通路。

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(±)2-(14,15-Epoxyeicosatrienoyl) glycerol Chemical Structure

(±)2-(14,15-Epoxyeicosatrienoyl) glycerol Chemical Structure

CAS No. : 848667-56-1

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(±)2-(14,15-Epoxyeicosatrienoyl) glycerol 相关抗体

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生物活性

(±)2-(14,15-Epoxyeicosatrienoyl) glycerol ((±)2-14,15-EG) is a novel CYP450 metabolite of 2-Arachidonoyl glycerol (2-AG) in the kidney. (±)2-(14,15-Epoxyeicosatrienoyl) glycerol is a potent mitogen for renal epithelial cells, increasing DNA synthesis in LLCPKcl4 cells. (±)2-(14,15-Epoxyeicosatrienoyl) glycerol activates the metalloprotease ADAM17, which cleaves proTGF-α and releases TGF-α as a ligand that initiates the EGFR-ERK signalling pathway[1].

分子量

394.54

Formula

C23H38O5
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

(±)2-(14,15-Epoxyeicosatrienoyl) glycerol 相关分类

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Keywords:

(±)2-(14,15-Epoxyeicosatrienoyl) glycerol848667-56-1(±)2-14,15-EGDNA/RNA SynthesisInhibitorinhibitorinhibit

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