1. Vitamin D Related/Nuclear Receptor
  2. Estrogen Receptor/ERR
  3. (±)-ErSO

(±)-ErSO 是 ErSO 的消旋体。ErSO 是选择性预期未折叠蛋白反应 (a-UPR) 激活物。

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(±)-ErSO Chemical Structure

(±)-ErSO Chemical Structure

CAS No. : 2407860-40-4

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规格 价格 是否有货 数量
1 mg ¥1590
1 - 2 周
5 mg ¥3500
1 - 2 周
10 mg ¥5800
1 - 2 周
50 mg   询价  
100 mg   询价  

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Customer Review

Other Forms of (±)-ErSO:

查看 Estrogen Receptor/ERR 亚型特异性产品:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

(±)-ErSO is the racemate of ErSO. ErSO is a selective anticipatory unfolded protein response (a-UPR) activator[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
HCT-116 IC50
0.093 μM
Compound: 1
Anticancer activity against ERalpha negative human HCT-116 cells assessed as cell growth inhibition incubated for 168 hrs by alamar blue assay
Anticancer activity against ERalpha negative human HCT-116 cells assessed as cell growth inhibition incubated for 168 hrs by alamar blue assay
[PMID: 35080871]
HCT-116 IC50
0.26 μM
Compound: 1
Anticancer activity against ERalpha negative human HCT-116 cells assessed as cell growth inhibition incubated for 72 hrs by alamar blue assay
Anticancer activity against ERalpha negative human HCT-116 cells assessed as cell growth inhibition incubated for 72 hrs by alamar blue assay
[PMID: 35080871]
HCT-116 IC50
11 μM
Compound: 1
Anticancer activity against ERalpha negative human HCT-116 cells assessed as cell growth inhibition incubated for 24 hrs by alamar blue assay
Anticancer activity against ERalpha negative human HCT-116 cells assessed as cell growth inhibition incubated for 24 hrs by alamar blue assay
[PMID: 35080871]
HT-29 IC50
0.21 μM
Compound: 1
Anticancer activity against ERalpha negative human HT-29 cells assessed as cell growth inhibition incubated for 24 hrs by alamar blue assay
Anticancer activity against ERalpha negative human HT-29 cells assessed as cell growth inhibition incubated for 24 hrs by alamar blue assay
[PMID: 35080871]
HT-29 IC50
0.25 μM
Compound: 1
Anticancer activity against ERalpha negative human HT-29 cells assessed as cell growth inhibition incubated for 72 hrs by alamar blue assay
Anticancer activity against ERalpha negative human HT-29 cells assessed as cell growth inhibition incubated for 72 hrs by alamar blue assay
[PMID: 35080871]
MCF7 IC50
0.014 μM
Compound: 1
Anticancer activity against ERalpha positive human MCF7 cells assessed as cell growth inhibition incubated for 72 hrs by alamar blue assay
Anticancer activity against ERalpha positive human MCF7 cells assessed as cell growth inhibition incubated for 72 hrs by alamar blue assay
[PMID: 35080871]
MCF7 IC50
0.02 μM
Compound: 1
Anticancer activity against human MCF7 cells assessed as cell growth inhibition incubated for 24 hrs by alamar blue assay
Anticancer activity against human MCF7 cells assessed as cell growth inhibition incubated for 24 hrs by alamar blue assay
[PMID: 35080871]
MDA-MB-231 IC50
23 μM
Compound: 1
Anticancer activity against ERalpha negative human MDA-MB-231 cells assessed as cell growth inhibition incubated for 24 hrs by alamar blue assay
Anticancer activity against ERalpha negative human MDA-MB-231 cells assessed as cell growth inhibition incubated for 24 hrs by alamar blue assay
[PMID: 35080871]
MDA-MB-231 IC50
6 μM
Compound: 1
Anticancer activity against ERalpha negative human MDA-MB-231 cells assessed as cell growth inhibition incubated for 168 hrs by alamar blue assay
Anticancer activity against ERalpha negative human MDA-MB-231 cells assessed as cell growth inhibition incubated for 168 hrs by alamar blue assay
[PMID: 35080871]
MDA-MB-231 IC50
8 μM
Compound: 1
Anticancer activity against ERalpha negative human MDA-MB-231 cells assessed as cell growth inhibition incubated for 72 hrs by alamar blue assay
Anticancer activity against ERalpha negative human MDA-MB-231 cells assessed as cell growth inhibition incubated for 72 hrs by alamar blue assay
[PMID: 35080871]
MDA-MB-436 IC50
14 μM
Compound: 1
Anticancer activity against ERalpha negative human MDA-MB-436 cells assessed as cell growth inhibition incubated for 72 hrs by alamar blue assay
Anticancer activity against ERalpha negative human MDA-MB-436 cells assessed as cell growth inhibition incubated for 72 hrs by alamar blue assay
[PMID: 35080871]
MDA-MB-436 IC50
22 μM
Compound: 1
Anticancer activity against ERalpha negative human MDA-MB-436 cells assessed as cell growth inhibition incubated for 24 hrs by alamar blue assay
Anticancer activity against ERalpha negative human MDA-MB-436 cells assessed as cell growth inhibition incubated for 24 hrs by alamar blue assay
[PMID: 35080871]
T47D IC50
0.01 μM
Compound: 1
Anticancer activity against human T47D cells harbouring ERalphaY537S mutant assessed as cell growth inhibition incubated for 24 hrs by alamar blue assay
Anticancer activity against human T47D cells harbouring ERalphaY537S mutant assessed as cell growth inhibition incubated for 24 hrs by alamar blue assay
[PMID: 35080871]
T47D IC50
0.015 μM
Compound: 1
Anticancer activity against human T47D cells harbouring ERalphaD538G mutant assessed as cell growth inhibition incubated for 24 hrs by alamar blue assay
Anticancer activity against human T47D cells harbouring ERalphaD538G mutant assessed as cell growth inhibition incubated for 24 hrs by alamar blue assay
[PMID: 35080871]
T47D IC50
0.02 μM
Compound: 1
Anticancer activity against ERalpha positive human T47D cells assessed as cell growth inhibition incubated for 24 hrs by alamar blue assay
Anticancer activity against ERalpha positive human T47D cells assessed as cell growth inhibition incubated for 24 hrs by alamar blue assay
[PMID: 35080871]
分子量

453.33

Formula

C22H13F6NO3

CAS 号
性状

固体

颜色

Light yellow to orange

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

产品名称:
(±)-ErSO
目录号:
HY-132247A
需求量: