2. Inhibitory Antibodies
  3. Racotumomab

Racotumomab  (Synonyms: 雷妥莫单抗; 1E10)

目录号: HY-P99254 纯度: ≥99.0%
COA

摩尔计算器

Racotumomab 是一种抗独特型单克隆抗体 (MAb)。Racotumomab 可与含有 Neu-glycolyl (NeuGc) 的神经节苷脂、硫苷脂和肿瘤中表达的其他抗原发生反应。Racotumomab 是一种抗癌剂，可用于肺癌的研究。

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CAS No. : 946832-34-4

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规格 价格 是否有货 数量
1 mg ￥2000
In-stock
5 mg ￥6000
In-stock
10 mg ￥8600
In-stock
25 mg ￥12178
In-stock
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100 mg   询价  

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Racotumomab 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Racotumomab (Anti-Human NGcGM3 Recombinant Antibody) is an anti-idiotype monoclonal antibody (MAb). Racotumomab reacts to Neu-glycolyl (NeuGc)-containing gangliosides, sulfatides, and other antigens expressed in tumors. Racotumomab is an active anticancer agent for lung cancer[1][2][3].

同型

Mouse IgG1 kappa
推荐同型对照抗体
种属

Mouse
体外研究
(In Vitro)

Racotumomab induces a specific humoral and cellular immune response against the NeuGcGM3 ganglioside present in tumor cells, stimulating the cell death[4].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Racotumomab 相关抗体:
体内研究
(In Vivo)

Racotumomab (50 μg/dose, i.p.) together with Keyhole limpet hemocyanin (KLH) inhibits tumor growth in F3II cell (s.c.) mammary tumor mice model[2].
Racotumomab (50 μg/dose, s.c.) together with Pemetrexed (100 mg/kg) is highly effective against lung nodules in 3LL cell (s.c.) mice xenograft[3].
Racotumomab (50-200 μg/dose, s.c.) shows no significant antitumor effect in 3LL cell (s.c.) mice xenograft[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 3LL cell (s.c.) mice xenograft[3]
Dosage: 50 μg/dose, together with Pemetrexed (100 mg/kg)
Administration: Subcutaneous injection (s.c.)
Result: Reduced lung nodules.
Clinical Trial
CAS 号
性状

液体

颜色

Colorless to light yellow

中文名称

雷妥莫单抗
运输条件

Shipping with dry ice.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • IgG1-kappa
纯度 & 产品资料
参考文献

Racotumomab 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Racotumomab946832-34-41E10雷妥莫单抗OthersTumorNSCLClung canceranti-metastaticNeuGcGM33LL cellF3II cellInhibitorinhibitorinhibit

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