2. TGF-beta/Smad
  3. TGF-β Receptor
  4. Ramatercept

Ramatercept  (Synonyms: ACE-031)

目录号: HY-P99818

摩尔计算器

Ramatercept (ACE-031) 是一种可溶的 ActRIIB 受体，能作为可溶性激活素受体 2 (ACVR2) 拮抗剂。Ramatercept 抑制肌生长抑制信号通路，在肌萎缩中有潜在应用。

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CAS No. : 1169766-01-1

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规格 是否有货
1 mg   询价  
5 mg   询价  
10 mg   询价  

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Ramatercept 相关抗体

Top Publications Citing Use of Products

查看 TGF-β Receptor 亚型特异性产品:

查看所有亚型
ALK1 ALK2 ALK3 ALK4 ALK5 ALK6 ALK7 TGFβR2 ACVR2A ACVR2B

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Ramatercept (ACE-031) is a soluble ActRIIB receptor and can be used as a soluble activin receptor 2 (ACVR2) antagonist. Ramatercept inhibits the signal pathway of muscle growth inhibition and has potential application in muscle atrophy[1][2][3].

IC50 & Target

soluble activin receptor 2, ACVR2[2]
体内研究
(In Vivo)

Ramatercept (ACE-031) (10 mg/kg；皮下注射；每周 3 次，持续 5 周) 显著增加了小鼠的肌肉量[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
CAS 号
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • [ACVR2B (activin A receptor type 2B, ActR-IIB, ActRIIB)]2-IGHG1 Fc (Fragment constant)
纯度 & 产品资料
参考文献

Ramatercept 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ramatercept1169766-01-1ACE-031ACE031ACE 031TGF-β ReceptorTransforming growth factor beta receptorsMuscle atrophyInhibitorinhibitorinhibit

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