1. Neuronal Signaling Metabolic Enzyme/Protease
  2. Sigma Receptor Proteasome
  3. RC-106

RC-106 是一种蛋白酶体抑制剂 (IC50: 35 μM) 和 Sigma 受体调节剂,具有抗癌活性。RC-106 对包括胶质母细胞瘤 (GB) 和多发性骨髓瘤 (MM) 在内的癌细胞具有抗增殖活性。

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RC-106 Chemical Structure

RC-106 Chemical Structure

CAS No. : 1346216-50-9

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  • 生物活性

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生物活性

RC-106 is a proteasome inhibitor (IC50: 35 μM) and Sigma receptor modulator with anticancer activity. RC-106 has antiproliferative activity against cancer cells including glioblastoma (GB) and multiple myeloma (MM)[1].

体外研究
(In Vitro)

RC-106 (60 μM; 24 h) 可抑制癌细胞活性[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay[1]

Cell Line: U87-MG cells
Concentration: 40, 60 μM
Incubation Time: 24 h
Result: Showed a moderate activity against U87-MG cells at 60 μM, reducing the cell viability to 34%。
分子量

355.52

Formula

C26H29N

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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RC-106
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HY-158197
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