Aconitase 2/ACO2 蛋白, Human (sf9, His-GST)

Aconitase 2/ACO2 Protein, an enzyme, plays a vital role in the tricarboxylic acid cycle and energy production. Dysregulation of Aconitase 2/ACO2 Protein has been associated with mitochondrial dysfunction and oxidative stress. Targeting Aconitase 2/ACO2 Protein may provide potential therapeutic strategies by regulating energy metabolism, reducing oxidative damage, and improving mitochondrial function. Aconitase 2/ACO2 Protein, Human (sf9, His-GST) is the recombinant human-derived Aconitase 2/ACO2 protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag. The total length of Aconitase 2/ACO2 Protein, Human (sf9, His-GST) is 753 a.a., with molecular weight of ~110 kDa.

乌头酸酶 2/ACO2 蛋白作为细胞过程中的关键催化剂，促进柠檬酸通过中间体顺乌头酸异构化为异柠檬酸。这种酶活性在关键代谢途径中发挥着重要作用，有助于柠檬酸循环中间体的动态调节。ACO2 蛋白在协调柠檬酸向异柠檬酸转化中的作用强调了其在维持细胞能量平衡和代谢稳态中的重要性。

The enzyme activity of this recombinant protein is testing in progress, we cannot offer a guarantee yet.

Human

Sf9 insect cells

N-His;N-GST

Q99798 (Q28-Q780)

50  [NCBI]

Approximately 110 kDa

Greater than 90% as determined by reducing SDS-PAGE.

溶液.

Lyophilized from a 0.2 μm filtered solution of 20 mM Tris, 500 mM NaCl, 10% Glycerol, pH 8.0, 0.3 mM DTT. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping with dry ice.